background

CHROMIUM PICOLINATE

CHROMIUM PICOLINATE

Chromium picolinate is a form of the mineral chromium that can be found in supplements. Commonly it is used to improve nutrient metabolism and produce weight loss.

A typical specification for Chromium Picolinate USP is:

Sr.No. Tests Specification  
1 Description A Red to pink coloured powder or Dark Red Colour powder.
2 Solubility Practically insoluble in 10 ml water and alcohol.
3 Identification
a) By IR
b) By chemical
A: Infrared absorption: - Determined by infrared spectrophotometry compare the spectrum with that obtained with Chromium Picolinate RS or with the reference spectrum of Chromium Picolinate.
B: To 5ml of a solution (1in250ml) in a test tube add 1ml of 5N sodium hydroxide and 10 drop of 30 per cent H2O2 and heat gently for about 2 minutes: a yellow colour develops.
4 Mesh Size 99.0% Passing Through 60 Mesh.
5 Bulk Density Not Less Than 0.45gm/ml.
6 Chloride Not More Than 0.06%
7 Loss on drying Not More Than 4.0%
8 Chromium Content Between 12.18 to 12.68 % on dried basis.
9 Heavy Metal
Lead
Arsenic
Mercury
Cadmium
Not more than 3.0 ppm
Not more than 1.0 ppm
Not more than 0.1ppm
Not more than 1.0 ppm
10 Sulphate Maximum 0.2%
11 Assay 98.0 to 102.0%on dried Basis substance
12 Microbial test:
a) Total Microbial Count/Total fungal Count
b)E.Coli
c) Salmonella
d) S.aureus
Less than 1000 CFU/gm
ess than 100 CFU/gm
Absent
Absent
Absent